X-ray diffraction is a powerful tool for determining the structure of crystalline materials – this is most often used for identification of unknown samples, such as in geology and earth sciences, or for studying protein structures in life sciences. It can also be used to determine the unit cell dimensions of a known crystal, or to measure the purity of a sample. (read more)
Ion channels are essential to key cellular processes including signal transduction, osmoregulation and maintenance of the membrane potential. They are therefore the targets of many clinically used drugs. (read more)
A wide variety of contaminants with the potential to cause harm to humans and animals can make their way into the environment. They can be found in the air, water and soil and may come from sources such as industrial waste, landfill sites, pesticides and pharmaceutical drugs. (read more)
Proteomics is playing an increasingly important role in the discovery of disease biomarkers and the identification of new therapeutic targets. Proteomics involves the separation, identification, and quantification of proteins. It also includes the characterization and analysis of proteoforms that arise as a result of post-translational modifications (PTMs) and sequence variants such as mutants and alternatively spliced isoforms. (read more)
Raman spectroscopy is a type of vibrational spectroscopy like the more widely used infrared spectroscopy. It measures the way light is scattered by a material. In most cases the wavelength of the scattered light is identical to the incident light and is known as Rayleigh scattering. (read more)
Spectroscopic methods exploit the interactions between matter and electromagnetic radiation in order to probe molecular fine structure. The way samples interact with radiation reveals a lot of information about its nature; making spectroscopy a useful tool for both qualitative and quantitative analysis. (read more)
The need for accurate cancer detection: The ability to distinguish cancer cells from healthy cells during surgery is essential for preventing the removal of healthy tissue and ensuring no tumor remnants are left behind. (read more)
Alzheimer’s disease is a progressive neurodegenerative condition that causes dementia. In this disease, dementia symptoms such as memory loss and difficulties with language, problem-solving and reasoning gradually worsen until they eventually start to interfere with everyday life and basic tasks such as eating and drinking. (read more)
Food allergies are a major public health concern and are increasing worldwide. Globally, it is thought that between 220 and 250 million people suffer from a food allergy. Ninety percent of cases involve sensitivity to one of the ‘Big Eight’ allergens: egg, fish, milk, peanut, shellfish, soy, tree nuts, or wheat. (read more)
Many consumers like to buy products marked as herbal or “natural”, often regarding these to be better for them, or even harmless. But, in reality, many such products are laced with unlabeled substances, which often includes pharmaceuticals that have long since lost their regulatory approval. (read more)
Two couples were awarded nearly $4.25 million on Thursday after a federal jury found one of the largest natural gas producers in Pennsylvania was responsible for the contamination of their well water, capping a six-year odyssey that turned their sleepy village into a battleground over the nation's shale drilling and hydraulic fracturing boom.
via News Medical
Male breast cancer (Male BC) has important biological differences that distinguish it from female breast cancer, but to date these have been little studied and Male BC patients have been excluded from many clinical trials in breast cancer. Male patients are also usually diagnosed later when their cancers are more advanced, leading to a worse outcome.
via News Medical
Cancer clinical trials with negative results don't make an immediate splash in the scientific literature, but they do have a long-term impact on cancer research, according to a new study by SWOG, the federally funded international clinical trials network. In results published in the latest issue ...
According to evolutionary theory, natural selection should remove inferior individuals from the population, and thereby erode diversity and promote monomorphism. New research published in the journal Scientific Reports demonstrates that polymorphism as such can be beneficial for both individuals and populations by offering protection against predators.
Anyone who has eaten roasted chicken can account for the presence of a long, spine-like bone in the drumstick. This is actually the fibula, one of the two long bones of the lower leg (the outer one). In dinosaurs, the ancestors of birds, this bone is tube-shaped and reaches all the way down to the ankle.
Tennis star Maria Sharapova has been provisionally suspended from competition after testing positive for the recently banned drug meldonium. But what exactly does this drug do, and can it really enhance athletic performance? On Monday (March 7), Sharapova admitted to failing a drug test for the upcoming Australian Open because she had been taking meldonium (sold under the brand name Mildronate).
via News Medical
The creation of a network of centres of reference and adopting measures that promote research and access to treatments are two key aspects for improving the prognosis of patients with soft tissue sarcoma (STS), an uncommon type of cancer that originates in the tissues that connect, support and surround other body structures, such as muscles, fat, blood vessels, nerves, tendons and lining of the joints.
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